Department of
Anesthesiology and Perioperative Medicine

Basic Research

Our current basic research focuses on mechanisms of anesthesia, pain, and neuronal injury and protection; alcoholism; and ventilator-induced lung injury.

 

embryo cytoplasmic microinjection

Alcohol Neurobiology and Genetic Engineering

Gregg Homanics, PhD

The Homanics Lab is interested in understanding the effects of alcohol on the body so that safe, effective treatments for alcohol use disorder can be developed.

slowing an over-excited heart rate with epidural anesthesia

Cardiac Anesthesiology

Aman Mahajan, MD, PhD, MBA

The Mahajan Lab’s primary research focus is spinal neural modulation of cardiac electrophysiology and the assessment of cardiac function in heart failure.

images from the Xu Lab

Mechanisms of General Anesthesia, Pain, and Neuronal Injury and Protection

Suzanne Doolen, PhD

Dr. Doolen's research objective is to understand the mechanisms that initiate and maintain chronic pain with the goal of developing therapeutic drug targets that outperform those currently available. 

Pei Tang, PhD

Research in the Tang Lab focuses on the action of low-affinity drugs, such as general anesthetics and alcohols, on the neurotransmitter-gated receptor channels.

Bradley K. Taylor, PhD

Dr. Taylor's laboratory investigates the mechanisms through which inflammation or injury produces changes in the peripheral nerves, spinal cord, and brain, leading to a transition from acute pain to chronic pain. 

Yan Xu, PhD

The Xu Lab research team is one of the leading groups in the world to combine high-resolution and solid-state NMR techniques to solve membrane protein structures at atomic resolution.

two-hit model: MV+CLP-sepsis

Ventilator-Induced Lung Injury (VILI)

Li-Ming Zhang, MD

Dr. Zhang’s current research focuses on identifying the susceptibility genes of VILI via an unbiased genome-wide association study in inbred mice and to evaluate its relevant functional significance.