Department of Anesthesiology

James W. Ibinson, MD, PhD

  • Assistant Professor

Education & Training

  • The Ohio State University, BS, Chemical Engineering
  • The Ohio State University School of Medicine, MD
  • The Ohio State University, PhD, Biomedical Engineering
  • University of Pittsburgh Department of Anesthesiology, T32 Postdoctoral Research Fellowship

Representative Publications

​Dr. Ibinson's publications can be reviewed through the National Library of Medicine's publication database.

Research, clinical, and/or academic interests

The chief focus of Dr. Ibinson's research is functional magnetic resonance imaging (FMRI) of pain processing. His work is focused on expanding the knowledge of how longer stimulations are processed and how this can be translated toward the understanding chronic pain. Clinical applications of FMRI toward pain are also being pursued. As detailed below, he is currently examining brain activation during accommodation to a painful stimulus, a novel technique for data normalization that may allow calculation of the blood oxygen level dependent (BOLD) effect across sessions, and a study of the functional connectivity of the brain while processing pain.

Past investigations have largely focused on experimentally induced acute pain because BOLD FMRI requires relatively rapid changes between "active" and "resting" states, and rapid alterations between chronic-pain and pain-free states are not easily accomplishable. Novel but complicated experiments are starting to emerge to identify the brain areas active during chronic pain. We have been working to develop a post-processing normalization method to allow across session BOLD studies with encouraging results, so that rapidly switching between states may not be necessary. This would open up an easy-to-implement analysis technique for the study of chronic pain.

Several labs have been able to show that small fluctuations in the BOLD FMRI signal are temporally correlated between various brain regions, even when the subjects are at rest. These correlations are believed to reflect brain organization, and illustrate the resting state connections (also termed functional connectivity). This new technique is being applied to pain research; functional connectivity has been shown to be altered in patients with diabetic neuropathic pain at rest. Dr. Ibinson has collected data for an investigation into functional connectivity during active pain processing, as opposed to processing in pain patients who are at rest. The goal with this work is to reveal new information into the accommodation phenomenon by highlighting areas whose functional connectivity grows with prolonged stimulation.