Dr. Jafri’s past research experiences include work in molecular, cellular, and behavioral neuroscience. During his undergraduate studies at University of California, Berkeley, he worked on neural circuits, cell morphology, and mouse behavior in the context of the primary somatosensory cortex. There, he completed an honor’s thesis examining the ability of Fragile-X Syndrome model mice to perform a dual-forced choice sensory discrimination task compared to healthy wild-type mice. During his graduate studies at Thomas Jefferson University, Dr. Jafri utilized molecular and advanced nanoscopy techniques to manipulate cultured rat primary cortical neurons and study their nanostructural and physiologic properties. His dissertation explored the role of the nanoscale organization of key synaptic proteins in synaptic signaling and function.
- MD, Sidney Kimmel Medical College
- PhD, Neuroscience, Jefferson College of Life Sciences
- BA, Molecular and Cell Biology, University of California, Berkeley
- BA, Philosophy, University of California, Berkeley
Education & Training
Jafri H, Thomas SJ, Yang SH, Cain RE, Dalva MB. Nano-organization of synapses defines synaptic release properties at cortical neuron dendritic spines. In Review (2025).
Rodriguez PFG, Lilach Y, Ambegaonkar A, Vitali T, Jafri H, et al. MAxSIM: multi-angle-crossing structured illumination microscopy with height-controlled mirror for 3D topological mapping of live cells. Commun Biol 6, 1034 (2023).
Ogunmowo TH, Jing H, Raychaudhuri S, Kusick GF, Imoto Y, Li S, Itoh K, Ma Y, Jafri H, et al. Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis. Nat Commun 14, 2888 (2023).
Hruska M, Henderson N, Le Marchand SJ, Jafri H, Dalva MB. Synaptic Nanomodules Underlie the Organization and Plasticity of Spine Synapses. Nat Neurosci 21, 671–682 (2018).
Elstrott J, Clancy KB, Jafri H, Akimenko I, Feldman DE. Cellular mechanisms for response heterogeneity among L2/3 pyramidal cells in whisker somatosensory cortex. J Neurophysiol, 112(2):233-248 (2014).