Department of
Anesthesiology and Perioperative Medicine

Charles C. Horn, PhD

  • Associate Professor of Medicine and Anesthesiology and Perioperative Medicine

Dr. Horn’s primary research focus is the neurobiology of vagus nerve signaling in health and disease; and, more generally, the role of gut-brain communication in homeostasis. Numerous medical treatments and diseases affect gut-brain interactions to elicit nausea and emesis, reduce food intake, induce inflammatory responses, and modulate pain; the laboratory conducts studies on the impact of cytotoxic chemotherapy agents, surgical drugs (anesthesia and analgesics), and chronic conditions (e.g., cancer) on these responses. This line of research has the long-term goal of developing treatments to decrease symptom burden and improve quality of life for patients.

Education & Training

  • Missouri State University, BS, Psychology
  • Kansas State University, PhD, Behavioral Neuroscience
  • Center for Neurobiology and Behavior, Columbia University, Postdoctoral Fellowship

Representative Publications

​Dr. Horn's publications can be reviewed through the National Library of Medicine's publication database.

Research, clinical, and/or academic interests

Mechanisms of nausea and vomiting

neural control of gut function

vagal signaling