“Preoperative Identification of Patient-Dependent Blood Pressure Targets Associated With Low Risk of Intraoperative Hypotension During Noncardiac Surgery,” by authors Michael Schnetz, MD, PhD, David J. Danks, PhD (Pitt Department of Biomedical Informatics), and Aman Mahajan, MD, PhD, MBA, was published as the “featured article” in the February 2023 issue of Anesthesia and Analgesia (A&A) and was spotlighted on the cover.
The authors developed a model that predicts personalized blood pressure targets for adult patients undergoing noncardiac surgery. Targets are based on a patient's individual characteristics, including age, gender, and co-morbidities at the time of surgery, and represent blood pressures with the lowest risks of future hypotension, an adverse event linked to vital organ system injuries and death. Clinicians may use the findings to identify which blood pressures are safest to maintain during surgery, thereby reducing a patient's risk of later complications. This work offers to advance perioperative care by making more personalized approaches to hemodynamic management possible.