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Gregory Rompala Receives NIAAA Grant to Study Effects of Drinking Alcohol across Generations

"Headshot of Gregory Rompala"

 

Gregory Rompala, a graduate student in the laboratory of Gregg E. Homanics, PhD, recently received a grant from the National Institute on Alcohol Abuse and Alcoholism. This National Research Service Award predoctoral fellowship will provide up to three years of funding for a project entitled “Epigenetic Mechanisms of Intergenerational Alcohol Drinking Behavior.” As a graduate student in the Center for Neuroscience at the University of Pittsburgh, Mr. Rompala will continue his doctoral dissertation studies that are focused on understanding the persistent effects of alcohol across generations. Previous work in the Homanics laboratory demonstrated that exposure of male mice to alcohol prior to mating produced male offspring that surprisingly consumed less alcohol and were more sensitive to the anxiolytic effects of alcohol. Mr. Rompala is currently investigating the molecular mechanism(s) that mediate these effects through the male germline. A detailed understanding of these mechanisms may provide novel molecular targets that can be therapeutically exploited to combat alcoholism.